After their encounter with Scar, Ed's automail and Al's armor need to be repaired, so Major Armstrong escorts them to their hometown of Risembool. On their way there, they spot Dr. Marcoh, a scientist who helped create the Philosopher's Stone, and try to convince him to give them the location of the Stone's research data.
Show: Fullmetal Alchemist: Brotherhood
Disregard for alchemy’s laws ripped half of Edward Elric’s limbs from his body and left his brother Alphonse’s soul clinging to a suit of armor. To restore what was lost, the brothers seek the Philosopher’s Stone. Enemies and allies – the corrupt military, the Homunculi, and foreign alchemists – will alter the Elric brothers course, but their purpose will remain unchanged and their bond unbreakable.
An Alchemist's Anguish
Ed and Al become interested in biological transmutation after witnessing a chimera in Lior, so Colonel Mustang introduces them to an expert in the field, Shou Tucker, the Life-binding Alchemist. Meanwhile, a serial killer whose targets are only State Alchemists is on the loose in Central.
City of Heresy
Ed and Al arrive at the city of Lior, hoping to find the legendary Philosopher's Stone so they can return their bodies back to normal. There, they meet a priest named Cornello, who is able to perform "miracles." As Ed and Al investigate, they find out the truth about Cornello.
The First Day
On the way to Lior, Ed and Al reminisce about the events that lead to them being trapped in their current bodies by breaking the taboo of human transmutation. Meanwhile, Colonel Mustang looks back on the first time he met the Elric brothers.