Transported to the world of XXXHolic, Syaoran, Kurogane, and Fai ask the Dimensional Witch Yûko to grant their wish. Syaoran's wish is to travel to many worlds to restore the memories of Sakura, Kurogane's wish is to return to his own world, and Fai's wish is to travel to different worlds to avoid his own. Though their intents are different, the method is the same and that is to travel between different worlds. However, they must all pay a price before their wishes can be granted. Kurogane's payment is his sword, Fai's payment is the marking on his back, and Syaoran's payment is his relationship with Sakura. Though hesitant about their payment, they pay up and are given Mokana Modoki to travel to the next world. After coming to, the gang find themselves in the middle of a gang war but instead of modern weapons, everyone is fighting with a special technique called a Kudan.
Event Year: 2005
Time After Time
Colin Marlow continues to try to get in the way of Cristina and Burke's relationship. The daughter that Izzie gave up for adoption needs something from her. This episode features a pro chess player, a flirtatious woman, and a mother named Mrs. Malone. Mr. and Mrs. Malone haven't talked to their daugther in a while because of their son-in-law. Someone goes to see a priest.
The Inevitable Encounter
A mysterious power within Sakura is awaken by the ruins as wings sprout from her back. Sakura beings to fade into the seal but Syaoran saves her. However, the wings break as the feathers scatter to many different worlds. Syaoran carries Sakura, now unconsciouses and her life fading away, out of the ruins to find themselves being attacked by mysterious mechanical warriors. Touya manages to keep them back as Yukito finds that Sakura's heart is no longer in this world. With no other choice, Touya leaves Sakura to Syaoran and Yukito sends the two to another world to seek help from the Dimensional Witch. Now in the world of XXXHolic, Syraoran is joined by Kurogane and Fai as he pleads to Yûko to save Sakura.
My Favorite Mistake
In the aftermath of Izzie's affair with George, he doesn't seem to remember anything. Callie lets him know that they will be having dinner with her father, but George does not make a good impression, being hung over after last night's events. Alex helps Jane Doe choose how her face will look like after Mark Sloan performs reconstructive surgery on her. He also gives her a new perspective on how the world will see her from then on. The hospital board begins interviewing the candidates for the Chief's position, and Colin Marlow intimidates everyone with his ten-year plan. However, after taking advice from Bailey, Mark seems to have convinced the board that he is appropriate for the job, despite continuous efforts from Derek, Burke and Addison, whose careers in the hospital outlast his. Izzie seeks advice from Addison about her affair, telling her sleeping with George felt right, despite him being married.